BPC-157 – The Regenerating Peptide
An article on all the interesting stuff about this regenerating peptide
What Is A Peptide, Again?
Peptides are short strings of amino acids, typically comprising 2–50 amino acids.
They are easier for the body to absorb than proteins because they are smaller and more broken down than proteins.
Therefore, they can more easily penetrate the skin and intestines, which helps them to enter the bloodstream more quickly.
Research peptides are any peptides that researchers use in scientific research.
In recent years, peptides have gained recognition as being highly selective and effective in therapeutic applications.
Research peptides are those synthesized for study in the lab that can lead to new breakthroughs and future pharmaceuticals, but they become medicines only after undergoing rigorous study, clinical trial, and crucially, the FDA approval process.
What Is That?
BPC-157 is a short peptide chain – essentially a piece of a protein. Its regenerative potential attracted scientists, who are starting to investigate if this peptide may promote muscle and wound healing.
It is a protein we can find in stomach acid. Researchers discovered it already in the ‘90s.
BPC 157 is a 15-amino-acid-long fragment of this protein.
It is synthetic because this particular sequence does not exist in nature.
Some studies refer to BPC as a “body protection compound” hinting at its therapeutic potential. Scientists consider it a blueprint for an entirely new class of organ-protective/healing drugs, but research is still in the early stages.
Researchers have conducted numerous rodent studies on BPC-157 that show it has protective effects extending beyond the stomach and intestinal tract.
BPC-157 has been shown to benefit ulcers in the stomach, intestinal damage such as fistulas and inflammatory disorders, bone and joint healing and growth rates, and organ damage.
We need more research to clarify whether BPC-157 has multiple mechanisms of action, but current research suggests BPC-157 influences several growth factors usually involved in angiogenesis (the production of blood vessels) and other factors involved in regeneration following damage.
In rats with injuries in their Achilles tendons, injections with BPC 157 helped the tendons to heal almost completely, whereas control rats didn’t make full recoveries.
Similarly, peptide injections improved muscle healing for rats whose muscles had been cut or crushed.
This effect even held true when rats were also treated with corticosteroids, which can slow the healing process.
BPC-157 is also sometimes called “The Wolverine Peptide”.
How does it work?
BPC 157 may promote muscle and tendon healing by triggering the formation of new blood vessels.
This explains its regenerative potential and why it might also help heal wounds, cuts, and other types of damage in the body.
Additionally, BPC 157 may promote wound and tendon healing by blocking the growth-inhibiting effects of a specific molecule called 4‐hydroxynonenal.
It might specifically help tendons heal by causing tendon cells to make more receptors for growth signaling molecules.
This, in turn, allows the tendon cells to grow and move during injury repair, speeding up the process.
It also reduces inflammation, which is involved in its effects on wounds, ulcers, and tissue protection.
Lastly, it can increase the production of nitric oxide (NO), which lowers blood pressure and helps to reduce the effects of high potassium levels.
So What Are All The Benefits Of This Wolverine Peptide?
Following most research reports we can state that the benefits of BPC-157 are:
- Accelerated wound healing (muscle, ligament, tendon, nerve)
- Decreases pain in damaged areas
- Increases growth hormone receptors
- Promotes the outgrowth of tendon fibroblasts, cell survival under stress, and the migration of tendon fibroblasts
- Improves digestive function
- Improves NO production
- Protects and heals inflamed intestinal epithelium
- Helps with Inflammatory Bowel Syndrome
- Protects the liver from toxic insults (alcohol, antibiotics, etc.) and promotes healing
Research shows peptides don’t have a lot of negative side effects.
And when we look at research info on BPC-157 there aren’t any notable side effects reported.
BPC-157 is a short peptide chain with a lot of regenerative properties.
Therefore it is often called the Wolverine Peptide.
It’s great if you are going for a research project that includes any kind of healing of muscles and tendons with extra inflammatory aspects.