MK-2866: Another Phase 3 Trial?

MK-2866: FDA Fast Track Designation Approved!

MK-2866: Another Phase 3 Trial?
Another Phase 3 trial for MK-2866 (or Enobosarm or Ostarine) is enrolling!

MK-2866: Another Phase 3 Trial?

Wait? What?

MK-2866 Going To Phase 3!

Yes, you are hearing this right.
Another Phase 3 trial is enrolling for our most beloved research compounds!

MK-2866 (Ostarine) is one of the most researched SARMs already and did undergo a lot of clinical trials upon to phase 2.
In the previous months, we already updated you about the first phase 3 trial, the ARTEST trial.
And today we can give you another update on a new phase 3 trial for Ostarine.

 

Enobosarm By Veru

MK-2866: Another Phase 3 Trial?

Veru is a big pharmaceutical company with some specific and progressive meds.
Therefore they do dare to take some well-thought-out risks towards the future.
Veru is also the company responsible for the first phase 3 trial for Ostarine, the ARTEST-trial, and is now enrolling in a second phase 3 trial!

You can read all about the first phase 3 trial here and here.

 

So What Is The Buzz About?

 

Well the FDA already agreed in October 2020 that further research for MK-2866 was allowed.
The FDA gave the permission to start up phase 3 clinical trials for Ostarine!

Now Veru announced that they will start a phase 3 clinical trial a few months ago.
This clinical trial is already underway as we speak.
The predicted end date for the trial is April 2023.

Now only a few months later Veru announces another phase 3 clinical trial for Enobosarm: the ENABLAR-trial

 

The ENABLAR-trial

Goal

The goal is to determine whether Ostarine is safe for human use.
Another goal is to study if Ostarine combined with another compound is a more effective way as a treatment for post-breast cancer therapy.
The ENABLAR-trial is a clinical study evaluating enobosarm + abemaciclib combination therapy as treatment of second-line metastatic AR+ER+HER2- breast cancer patients whose breast cancer has progressed after treatment with palbociclib and either a nonsteroidal aromatase inhibitor or fulvestrant combination.

Research Length

This will be a very detailed phase to determine safety and efficacy.
The Phase 3 ENABLAR-2 clinical trial was expected to begin enrollment in calendar Q4 2021.
The endpoint has yet to be determined but you can expect it will take a little less than 2 years.
Therefore, the endpoint of the research Phase could be fall of 2023.

The Details

There are not a lot of details available right now.
The only thing we know for sure is that Phase 3 ENABLAR-2 study wants to evaluate the efficacy and safety of enobosarm and CDK 4/6 inhibitor, abemaciclib, combination compared to estrogen-blocking agent (Active Control) for the treatment of AR+ER+HER2- metastatic breast cancer (≥ 40% AR positivity) in a second-line metastatic setting in approximately 186 patients who have failed 1st line treatment in a metastatic setting with CDK 4/6 inhibitor, palbociclib, in combination with either an aromatase inhibitor or fulvestrant.

Again the primary goal is efficacy, secondary safety.
The hope is that this trial will help to develop a new novel endocrine therapy for our patients that will help effectively treat their cancers and delay the time to transition to chemotherapy.

We will provide you with updates when more details are available.

Short Recap

Another Phase 3 trial is enrolling for our most beloved research compounds!
Not all the details are available yet but the most important goal is as well to determine that Ostarine is safe to use and that it is more efficient than older methods.
The rest of the details you will find above.
The trial was expected to begin enrollment in calendar Q4 2021 so we can expect it starts soon.

We will follow these developments thoroughly and keep you up to date about future results!

 

As an extra for our Knowledge Vault, we will do more news flashes regarding all of our research compounds.
So you always can find all the latest info about these compounds here!

MK-2866: Another Phase 3 Trial?

Don’t forget: at Rat’s Army, you will find these products in the best quality around, at competitive pricing, and in multiple variants!
Make sure you visit our shop soon to start your own research with these wonderful compounds!

Leave a Reply

Your email address will not be published. Required fields are marked *