Oh no, my SARMs have crystallized! What now?
We all know the lovely feeling when your package finally arrives.
So you open it with a feeling of joy inside, you fill your dropper and all of the sudden, you see crystals…
What now? Is my package ready for the garbage?
Of course not. Just read this article.
First of all: what is crystallization?
Crystallization is the (natural or artificial) process where the atoms or molecules are highly organized into a structure known as a crystal. Some of the ways by which crystals form are precipitating from a solution, freezing, or more rarely deposition directly from a gas. Attributes of the resulting crystal depend largely on factors such as temperature, air pressure, and in the case of liquid crystals, time of fluid evaporation.
Crystallization occurs in two major steps: the first is nucleation, the appearance of a crystalline phase from either a supercooled liquid or a supersaturated solvent and the second step is known as crystal growth, but that one isn’t important here.
In short: crystallization is the process from a liquid to a (more) solid form most occuring under temperature changes (cooling).
So what is nucleation?
Nucleation is simply defined as the first random formation of a distinct thermodynamic new phase (daughter phase or nucleus (an ensemble of atoms)) that have the ability to irreversibly grow into larger sized nucleus within the body of a metastable parent phase.
Nucleation is of two types: homogeneous nucleation and heterogeneous nucleation.
Homogeneous nucleation does not involve foreign atoms, particles or surfaces. Heterogeneous nucleation is achieved through the influence of foreign particles and/or surfaces.
In the case of the problem with our SARMs we have to look in to the heterogeneous nucleation. One of the best known examples of heterogeneous nucleation is the formation of ice.
In short: nucleation is the first step in the crystallization process and forms small nuclei (smaller compounds that start bounding) who may form crystals.
But what does it mean for my products…
When we look in to our problem, we have to look in to the basics of these processes. Crystals from nucleation are most often formed by fluctuations in temperatures. So when the temperature drops there is always a chance that crystals will form.
In case of liquid solutions like these, the chances are even higher because they are very pure and they are first mixed in higher temperatures so need to cool down a lot. They also experience big (and sometimes for a longer time) drops in temperature when they are being shipped across the country of world.
So you could say, to put it in a simple way, that the crystallization of these products resembles the most on the most easy form of crystallization we know: the forming of ice. But it can happen at less lower temperatures. It just happens when the liquid cools down in a slow way at ‘constant’ temperature.
In short: high quality pharmaceutical grade products are prone to crystallization because of the process of mixing them and the process of shipping them all over the world.
Is there a solution? And is my product still the same quality?
Yes and yes. The solution is really simple: we just reheat the compound really slowly in a constant way. The best way to do it is to boil some water, and put your vial/bottle in it for a maximum of 5 minutes. Afterwards you shake your vial/bottle in a controlled manner so your crystals will dissolve completely..
We should note that the temperature of the boiling water will not affect your solution as many of these chemicals have melting points up to 420 degrees celsius.
In terms of quality, nothing changes. Crystallization does not alter the quality of the original liquid form.
In this case, the compound isn’t even exposed at really low temperatures but the compound is prone to crystallization. As long as you reheat slowly, there will be no quality loss whatsoever.
In short: just click this link 🙂
Don’t worry. It just means that you have a product of extremely good quality.
These compounds are just prone to these processes. But nucleation nor crystallization alters the quality of your products.
Just follow our reheating guidelines and you are ready again to start your research!