Our AIs: A Quick Guide!

Our AIs: A Quick Guide!

Our AIs: A Quick Guide!
Read all you need to know about the AIs we offer and how to use them for your research!

Exemestane Sour Apple Anastrazole Sour Apple

AI? What Is That?

Mechanism of forming Estrogen

Aromatase inhibitors (AIs) are a class of medicines that work by blocking the enzyme aromatase, the enzyme that converts androgens into estrogen.
We use aromatase inhibitors in the treatment of breast cancer to reduce levels of circulating estrogen.

So they lower estrogen levels by stopping an enzyme in fat tissue from changing other hormones into estrogen.

There are three aromatase inhibitors: anastrozole, exemestane, and letrozole.

Since AIs lower estrogen, they are an excellent way to help in the fight against gynecomastia. By blocking estrogen, these kinds of breast tissue will not be able to grow.


Why Should You Use An AI?

Our AIs: A Quick Guide!


Mechanism of forming Aromatase Inhibitor








There are a few reasons why you should use an AI. The most obvious one is to block out estrogen. In the case of our sorts of research, AIs can be very helpful in some situations.

We all know we need estrogen in our body for several reasons (strong bones, healthy joints, sexual performance…).
But we also know that too high estrogen levels can be very counterproductive for our research. High estrogen levels can cause gynecomastia, water retention and a lot of other feminine features.

In most cases, our body is very efficient in regulating the balance of our testosterone/estrogen levels, but there are some situations where our body might need some help.

Highly Aromatising Compounds

When you start your research with a (or more) highly aromatizing compound, you should get an AI right away as a research auxiliary.
Aromatizing compounds will cause estrogen levels to rise too much for your body to regulate them properly.
This means your estrogen levels will be sky high and your testosterone/estrogen balance will be out of balance.
As these compounds keep lowering your own testosterone levels, you will be extra vulnerable to these high estrogen levels down your cycle and especially after your cycle.

So always check for the aromatizing nature of the compound. If it does aromatize, be sure to have an AI on hand.


Early Gynaecomastia

People who are prone to gynecomastia should always consider having an AI on hand when they start any form of research.
If you already experienced gynecomastia or can see your natural predisposition in your physique, don’t hesitate to take the right precautions.

The best part of an AI is that it works fast and blocks out any aromatizing in your body.
And that is what you want in case of early signs of gynecomastia.
By blocking out estrogen, soft breast tissue can’t grow.

So an AI is far more effective in this battle than a SERM (maybe except for Raloxifene) since it blocks out all aromatizing in your body.
A SERM only prevents estrogen to attach easily to the estrogen receptors. Some SERMs (like Raloxifene and Tamoxifen) are also good in blocking the attachment to receptors in the breast tissue.
We will give you some pro tips about this further down this article.


Stacking Suppressive Compounds

When stacking suppressive compounds, this means that your exogenous testosterone will rise very strong.
The excess of incoming testosterone in your body will cause a serious drop in SHBG and will kick your endogenous testosterone out of your androgen receptors.
The effect of this will cause a boost in free testosterone. This overload of free testosterone will aromatize causing estrogen levels to go way up.
In this case, it will be very useful to have an AI on hand for the first weeks of your cycle to counteract this situation.


When Should You Use An AI?

This is more about the timing than about in which situations.
The use of an AI will be pretty much the same in all of these above situations.

  • Take your AI once a day at the same moment
  • You need your AI especially at the start of your research
  • Only use your AI when you need it

Pretty simple, right.
AIs are dosed once a day so that’s the easy part.
As we mentioned before the moment you will need your AI will be in most cases at the beginning of your cycle. When using highly aromatizing compounds you will need it throughout the cycle.

If one of the above situations is applicable to you: you need an AI on hand.

Our pro tip: when you experience gynecomastia (and you are prone to it) you should go for the combination of an AI and Tamoxifen to have the best effect on solving your problem!


The AIs We Have For You

AnastrozoleOur AIs: A Quick Guide!

Anastrozole (a.k.a. Arimidex) is FDA approved to treat postmenopausal women with breast cancer that responds to estrogen-receptor treatment. It is primarily used to treat women with advanced disease progression, especially if they have received tamoxifen treatment before. It can also be used as first-line therapy as well.

The dosage for Arimidex is 1 mg once daily with or without a meal.


ExemestaneOur AIs: A Quick Guide!

Exemestane (a.k.a. Aromasin) is FDA approved to treat estrogen-receptor-positive breast cancer in postmenopausal women after 2 to 3 years of tamoxifen therapy. It is primarily used to treat the advanced progression of breast cancer after tamoxifen treatment has failed.

The dosage for Exemestane is 25 mg once daily after a meal.



Which One Should You Pick?

Both of these products are FDA approved so they both are safe to use.
They are very similar so have the same benefits and almost the same side effects.
They both block out aromatizing in a very efficient way.
The only differences are that Exemestane has fewer known side effects and that you should only combine Exemestane with Tamoxifen in your battle with gynecomastia (Arimidex might have interference with Tamoxifen).

Our AIs: A Quick Guide! Our AIs: A Quick Guide!












Don’t forget: at Rats Army you will find these products in the best quality around, at competitive pricing, and in delicious flavors!
Make sure you visit our shop soon to start your own research with these wonderful compounds!

Leave a Reply

Your email address will not be published. Required fields are marked *