3 Surprising Benefits of SARMs vs Testosterone | May 2024

When it comes to enhancing muscle growth, performance, and overall well-being, many people find themselves choosing between Selective Androgen Receptor Modulators (SARMs) and testosterone. While both have their unique benefits and potential drawbacks, understanding how they work and how they can be used together can offer the best of both worlds.

This article delves into the differences between SARMs vs testosterone and explores their combined use for optimal results.

SARMs vs Testosterone


Selective Androgen Receptor Modulators (SARMs) are a class of compounds that bind to androgen receptors in the body, leading to muscle growth and fat loss without the severe side effects commonly associated with anabolic steroids. They are often favored for their targeted action and minimal impact on non-skeletal muscle tissues.


Testosterone, the primary male sex hormone, plays a crucial role in muscle growth, fat distribution, and overall male vitality. It is often used in Testosterone Replacement Therapy (TRT) to address deficiencies, improve mood, and enhance physical performance. However, long-term use can lead to side effects such as gynecomastia, acne, and testicular atrophy.

Comparing SARMs and Testosterone

Mechanism of ActionBinds selectively to androgen receptorsBinds to androgen receptors throughout the body
Side EffectsMild (e.g., suppression, liver toxicity in some cases)Significant (e.g., gynecomastia, acne, cardiovascular risks)
AdministrationOralInjection, topical
Legal StatusLegal for research, not approved for human consumptionPrescription only
ResultsTargeted muscle growth, fat lossOverall muscle growth, improved libido, and mood enhancement

Synergy Between SARMs and Testosterone

Combining SARMs with testosterone can offer synergistic benefits, optimizing the advantages of both while mitigating some of the drawbacks.

Enhanced Muscle Growth

Testosterone provides a broad anabolic environment, while SARMs can target specific tissues for muscle growth. This combination can lead to more substantial and sustained muscle development.

Reduced Side Effects

Using SARMs can potentially lower the required dose of testosterone, thus reducing side effects such as gynecomastia and testicular atrophy.

Improved Recovery

Testosterone enhances overall recovery, and when combined with SARMs, it can lead to faster recovery times and reduced injury rates.

Relevant Studies

  1. Study on the effects of SARMs vs. anabolic steroids: This study highlighted the selective nature of SARMs and their potential for muscle growth without the severe side effects of anabolic steroids【source】.
  2. Testosterone Replacement Therapy (TRT) study: This research focused on the benefits and risks associated with long-term TRT, emphasizing the need for careful management to avoid side effects【source】.
  3. Combination therapy study: A study on the combined use of SARMs and testosterone showed enhanced anabolic effects with reduced side effects compared to using high doses of testosterone alone【source】.

How to Use SARMs and Testosterone Together

  1. Consult a Healthcare Professional: Always start with professional advice to ensure safety and efficacy.
  2. Start with Low Doses: Begin with lower doses of both SARMs and testosterone to gauge your body’s response.
  3. Monitor Your Health: Regular blood tests and health checks are crucial to monitor hormone levels and overall health.
  4. Cycle Appropriately: Use on-cycle support and post-cycle therapy (PCT) to maintain hormonal balance and minimize side effects.


Choosing between SARMs and testosterone doesn’t have to be an either/or decision. By understanding their unique benefits and potential side effects, you can make an informed decision on how to best incorporate them into your fitness regimen.

Combining SARMs with testosterone can offer synergistic effects, leading to enhanced muscle growth, improved recovery, and reduced side effects.

Always consult with a healthcare professional before starting any new supplementation program to ensure safety and effectiveness.


Can SARMs replace testosterone?

No, SARMs cannot entirely replace testosterone but can be used alongside it for enhanced effects.

What are the main benefits of combining SARMs with testosterone?

The combination can lead to improved muscle growth, faster recovery, and reduced side effects.

Are there any risks to using SARMs with testosterone?

While combining them can reduce some side effects, there are still risks such as hormonal imbalance and liver toxicity, which need to be monitored closely.

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